TypeTuple!(T...) vs Tuple!(T...)

[rsw0x via Digitalmars-d-learn]

exactly what is the difference here?

I have a rather large CTFE-generated TypeTuple in one of my 
structs in my project, and I can seemingly replace it with a 
Tuple with absolutely zero differences... except I compile about 
60-70% slower.

The tuple page is even confusing me
http://dlang.org/tuple.html

>A variable declared with a TypeTuple becomes an ExpressionTuple:
>alias TL = Tuple!(int, long);

is it using Tuple!(T...) and TypeTuple!(T...) interchangeably?