Debugging InvalidMemoryOperationError

[Sam via Digitalmars-d-learn]

I am building the open source project Sambamba with LDC and 
running its tests. If I build it in debug configuration (-g in 
place of -O2) then I get an InvalidMemoryOperationError. This 
does not occur in release configuration.

Various different platforms and debuggers (Linux, OS X, GDB, 
LLDB) give different quality de-mangling and stack trace output, 
but none seem to give local variables. Versions:

LDC - the LLVM D compiler (1.0.0):
   based on DMD v2.070.2 and LLVM 3.8.0
   built with DMD64 D Compiler v2.071.1
   Default target: x86_64-unknown-linux-gnu

Here is the stack from GDB (7.6.1-80.el7) on Linux:

#0  0x0000000000670a50 in onInvalidMemoryOperationError ()
#1  0x000000000068657b in gc.gc.GC.malloc() ()
#2  0x000000000067a4d2 in _d_newclass ()
#3  0x0000000000670d53 in _d_assert ()
#4  0x000000000053d8e2 in 
std.typecons.__T10RefCountedTS4cram8wrappers54__T5RcPtrTS4cram6htslib10cram_sliceS15cram_free_sliceZ5RcPtr7PayloadVE3std8typecons24RefCountedAutoInitializei0Z.RefCounted.__dtor() ()
#5  0x00000000005d39e6 in 
cram.wrappers.__T5RcPtrTS4cram6htslib10cram_sliceS15cram_free_sliceZ.RcPtr.__fieldDtor() ()
#6  0x000000000043a5e4 in cram.wrappers.CramSlice.__fieldDtor() ()
#7  0x00000000005d4ce2 in 
cram.wrappers.UndecodedSliceRange.__fieldDtor() ()
#8  0x000000000067c20e in rt_finalize2 ()
#9  0x000000000068935a in gc.gc.Gcx.sweep() ()
#10 0x0000000000687a1b in gc.gc.Gcx.fullcollect() ()
#11 0x0000000000687bae in gc.gc.GC.fullCollectNoStack() ()
#12 0x000000000067922b in gc_term ()
#13 0x0000000000679efa in rt_term ()
#14 0x000000000067a170 in _d_run_main ()
#15 0x0000000000414278 in main ()

Questions:

* does this suggest that an assert in the destructor of 
std.typecons.RefCounted is trying to allocate memory?
* if so, is this considered a bug?
* the wiki suggests that you need a debug build of the standard 
library to get accurate stack traces. is this just for line 
numbers or could the stack be completely wrong?
* any further suggestions as to finding the cause of this problem?